CYTOTOXIC POTENTIAL OF STIMULATED HUMAN LYMPHOCYTES
نویسندگان
چکیده
منابع مشابه
Cytotoxic Potential of Stimulated Human Lymphocytes
Viable and immunologically competent lymphocytes from unsensitized donors damage allogeneic tissue culture cells in the presence of phytohemagglutinin (PHA). This cytotoxicity is specific since syngeneic tissue culture cells are not at all or only slightly damaged under similar experimental conditions. In this investigation, the relation between the stimulation of human lymphocytes and their cy...
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Lymphocytes from tmsensitized animals or humans damage allogeneic cells in tissue culture when aggregated to the latter by means of phytohemagghtinin (PHA) (1-3). Under the experimental conditions used, injury of the target cells was not seen or was slight in the absence of PHA. When the PHA-treated lymphocytes were separated from the target cells by a Millipore falter, cell damage was prevente...
متن کاملCytotoxic Potential of Stimulated
Lymphocytes from tmsensitized animals or humans damage allogeneic cells in tissue culture when aggregated to the latter by means of phytohemagghtinin (PHA) (1-3). Under the experimental conditions used, injury of the target cells was not seen or was slight in the absence of PHA. When the PHA-treated lymphocytes were separated from the target cells by a Millipore falter, cell damage was prevente...
متن کاملCytotoxic Effects of Bisphenol A as an Endocrine Disruptor on Human Lymphocytes
Background: Endocrine compounds, such as Bisphenol A (BPA), stimulate or inhibit the activities of hormones, nuclear receptors in the central nervous system, liver and other organs. They may be disposed of in the environment inadverdently around industrial sites. The aim of this study was to evaluate the cytotoxic effects of BPA on human lymphocytes in culture at varying concentrations. Method...
متن کاملAdenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.
The association of a human genetic deficiency of adenosine deaminase activity with combined immunodeficiency prompted a study of the effects of adenosine and of inhibition of adenosine deaminase activity on human lymphocyte transformation and a detailed study of adenosine metabolism throughout phytohemagglutinin-induced blastogenesis. The adenosine deaminase inhibitor, coformycin, at a concentr...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1967
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.125.4.721